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Can CBD Help Manage Ankylosing Spondylitis Symptoms? Cannabidiol (CBD) can scale back inflammation and ache in arthritis and similar circumstances. Ongoing analysis is exploring its effect on ankylosing spondylitis (AS) specifically. AS, a rheumatic condition affecting the spine, often results in inflammation and persistent pain. That is regardless of standard treatments like nonsteroidal anti-inflammatory drugs (NSAIDs). As a result, some people seek different remedies, reminiscent of CBD. This is a non-euphoric compound from the cannabis plant. Around 20% of people with rheumatic conditions report utilizing cannabis for relief. Anecdotal experiences recommend that CBD may have some benefits for AS and similar situations, however scientific analysis remains limited. Here’s what we at the moment perceive. Can CBD assist handle ache in AS? Research on whether CBD might help handle ache in AS is lacking. That mentioned, analysis suggests that CBD may be an efficient tool for managing chronic ache. More analysis is needed to grasp the role that it could actually play in managing AS pain signs specifically.
For example, endocannabinoids produced by your physique might bind to immune cell receptors to let your physique know it’s experiencing inflammation. When endocannabinoids have performed their job, enzymes break them down. Again, experts don’t actually know the exact mechanisms behind how CBD interacts with the ECS. Still, they’re aware that CBD binds otherwise to CB1 and CB2 receptors in contrast with THC - presumably by preventing the breakdown of endocannabinoids. Experts additionally suspect that CBD produces more noticeable results when paired with THC. That’s why full-spectrum and broad-spectrum merchandise are extra seemingly to offer advantages than ones containing CBD isolate. This is known as the entourage effect. Can CBD assist deal with tinnitus? Research on CBD for tinnitus is blended. A 2015 animal study prompt that a mix of CBD and THC may actually make tinnitus worse. A newer overview of studies from 2020 concluded there’s not sufficient scientific proof from both animal or human studies to affirm that cannabinoids can assist relieve tinnitus. This has 
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